GLOSSARY

Testosterone and SHBG Laboratory Assessment
Testosterone assessment requires compatible symptoms, appropriately timed repeat measurements when indicated, and attention to SHBG.

Separate biological and analytical effects

Hormone results depend on secretion rhythms, binding, clearance, sample handling and the measurement method. Reference intervals and decision thresholds serve different purposes. Assay-specific interpretation is especially important near low concentrations and when results conflict with the clinical picture.

Interpreting the mechanism

• Total and free testosterone can diverge when binding proteins change, and reliable analytical methods are especially important at low concentrations.

Define the testing question

Dynamic tests examine a regulated response under specified conditions. Their protocols, contraindications and thresholds require clinical oversight. A glossary explanation supports understanding and does not provide a self-testing or medication-adjustment protocol.