GLOSSARY

Testosterone and Satellite Cell Activity
Androgens can influence satellite-cell behavior in appropriate experimental and physiological contexts.

Production, transport and local action

Androgen action depends on central gonadotropin drive, gonadal production, binding proteins and tissue-specific metabolism. Conversion to DHT or estradiol changes the local signal. Receptor expression and cofactors determine how exposure becomes a response in each organ.

Specific considerations

• Contributions depend on loading, age and exposure; blood testosterone alone does not quantify satellite-cell activity.

Interpreting androgen status

Symptoms, repeated appropriately timed measurements and relevant LH, FSH and SHBG results help distinguish endocrine patterns. A transient exercise-associated change does not predict hypertrophy. Exogenous androgen exposure can suppress endogenous regulation and fertility despite high circulating concentrations.