GLOSSARY

Prolactin Biosynthesis and Secretion
Prolactin biosynthesis involves gene expression and protein production in anterior pituitary lactotrophs. The hormone is processed and packaged for regulated secretion.

Release control

Dopamine provides tonic inhibition, while estrogens and physiological sensory inputs can increase lactotroph activity. Cellular electrical and calcium signals influence exocytosis.

State-dependent production

• Pregnancy and lactation alter both secretory activity and the size or function of the lactotroph population.
• Baseline expectations therefore differ across reproductive states.

Measurement boundary

A high circulating concentration can reflect altered production, release, removal or assay-related factors. Understanding biosynthesis helps frame the question, but concentration alone does not identify which step has changed.