GLOSSARY

Placental Growth Factor (PlGF)
PlGF is a placental-associated angiogenic factor whose measurement can support selected obstetric assessments.

Maternal, placental and fetal integration

Pregnancy changes hormone production, binding, clearance and target-tissue responsiveness. Maternal, placental and fetal tissues contribute different components. Expected laboratory patterns therefore depend on gestational stage and the analytical method, rather than nonpregnant reference values alone.

Specific considerations

Interpretation depends on gestational timing, method and validated clinical use.

Transitions around birth

Placental delivery rapidly changes steroid exposure, while prolactin-related synthesis and oxytocin-mediated ejection support lactation. These are coordinated but distinct mechanisms. Clinical problems during pregnancy or postpartum require interpretation within their specific maternal and fetal context.