GLOSSARY

ACTH Stimulation Test
An ACTH stimulation test evaluates adrenal cortisol responsiveness to administered ACTH using a defined sampling protocol.

Separate biological and analytical effects

Hormone results depend on secretion rhythms, binding, clearance, sample handling and the measurement method. Reference intervals and decision thresholds serve different purposes. Assay-specific interpretation is especially important near low concentrations and when results conflict with the clinical picture.

Interpreting the mechanism

• Its interpretation is assay-dependent, and recent central adrenal insufficiency can be difficult to identify before adrenal responsiveness has declined.

Define the testing question

Dynamic tests examine a regulated response under specified conditions. Their protocols, contraindications and thresholds require clinical oversight. A glossary explanation supports understanding and does not provide a self-testing or medication-adjustment protocol.