Salivary Amylase
Gastrointestinal System
Salivary amylase (ptyalin) is an enzyme secreted mainly by the parotid gland that begins the chemical digestion of starch in the mouth; it breaks alpha-1,4 glycosidic bonds, converting starch into maltose, maltotriose, and dextrins.
Characteristics
- Optimal pH: about 6.7–7; it is gradually inactivated by stomach acid but remains active inside the bolus for a while (about 30–60 minutes).
- Contribution: about 5–30 percent of starch digestion; most is carried out by pancreatic amylase in the small intestine.
- Cofactor: the chloride ion.
Genetics and Evolution
The number of AMY1 gene copies varies between people (2–15 copies or more); populations with
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